Stafforst group - Chemical Biology & Biochemistry of Nucleic Acids

Nucleic acids are fantastic molecules. They offer a playground to create novel materials and to manipulate biological systems. Due to their unique base pairing properties, hybridization between nucleic acids is highly predictable and thus rationally programmable. In our research we develop artifical, RNA-guided machines with the intention to create tools for the study and control of basic biochemical processes like RNA processing, translation, or epitranscript-omics. To achieve our goals, we combine chemistry with biotechnology and create tools that we finally apply inside cells and living organisms.




News & Jobs


Heisenberg-Professorship (W3) granted by the DFG


ERC Consolidator Grant 2014


To apply

Highly motivated students that like to tackle problems at the interface of chemistry and biology are cordially invited to join the group for their Bachelor or Master research.

For PhD or Postdoc applications, please send in a full application including at least a full CV (including current address and position), credentials, a motivation letter, and two references.


! open position !

Currently, we are looking for a PhD student interested in exploring the therapeutic application of SNAP-deaminases.




Member of  the

Dechema Zukunftsforum"